Cost-Effective Private Linear Key Agreement With Adaptive CCA Security from Prime Order Multilinear Maps and Tracing Traitors

Private linear key agreement (PLKA) enables a group of users to agree upon a common session key in a broadcast encryption (BE) scenario, while traitor tracing (TT) system allows a tracer to identify conspiracy of a troop of colluding pirate users. This paper introduces a key encapsulation mechanism in BE that provides the functionalities of both PLKA and TT in a unified cost-effective primitive. Our PLKA based traitor tracing offers a solution to the problem of achieving full collusion resistance property and public traceability simultaneously with significant efficiency and storage compared to a sequential improvement of the PLKA based traitor tracing systems. Our PLKA builds on a prime order multilinear group setting employing indistinguishability obfuscation (iO) and pseudorandom function (PRF). The resulting scheme has a fair communication, storage and computational efficiency compared to that of composite order groups. Our PLKA is adaptively chosen ciphertext attack (CCA)-secure and based on the hardness of the multilinear assumption, namely, the Decisional Hybrid Diffie-Hellman Exponent (DHDHE) assumption in standard model and so far a plausible improvement in the literature. More precisely, our PLKA design significantly reduces the ciphertext size, public parameter size and user secret key size. We frame a traitor tracing algorithm with shorter running time which can be executed publicly

Urological disorders and pregnancy: An overall experience

Aim: Pregnancy is an anatomical and physiological altered state and the presence of various urological problems not only aggravates the disease itself, but also results in unfavourable pregnancy outcome. Aim is to highlight obstetric outcome in pregnant women with urological problems. Materials and Methods: Longitudinal prospective cohort study conducted in tertiary care hospital, IPGME and R, Kolkata from Jan 2011 to Dec 2012. All pregnant women with urological problems were included as subjects. Results: A total of 33 subjects were followed up throughout their antenatal period. Among them majority (72.72%) presented with hydro nephrosis followed by hydroureter (60.6%), PUJ obstruction and pyelonephritis each with incidence of 15.15%, then urolithiasis (12.12%), nephrolithiasis (6.06%) and renal abscess (12.12%). Interventions required were DJ stenting (72.72%), pyeloplasty (15.15%) and others were RURSL, abscess drainage and ATT. The pregnancy outcome was complicated with preterm labor in majority of patients (45.45%), oligohydramnious (18.18%), PIH (9.09%) and still birth (6.06%). Twenty four live birth were there. Majority required NICU admissions as predominantly prematurity was an important concern. Majority women with hydronephrosis underwent DJ stenting. Conclusion: Preterm labor is an important obstetric concern. Vaginal delivery is the choicest mode of termination and LSCS can be reserved for obstetric reason. DJ stenting is safe and practical approach for continuation of pregnancy with hydronephrosis. Regular follow up, vigilant antenatal care and multidisciplinary approach from urologist, obstetrician and neonatologist will bring out successful pregnancy outcome

Investigation on chemical protease, nuclease and catecholase activity of two copper complexes with flexidentate Schiff base ligands

Two new Cu(II) complexes [Cu(HL)(MeOH)(Py)](ClO4)2 (1), [Cu(HL)(DMF])(NO3)2 (2) have been synthesized from Schiff base ligand [HL = 2-(phenyl((2-(piperazin-1-yl)ethyl)imino)methyl)phenol ] with flexible piperazinyl moiety. Structural analysis reveals that 1 and 2 are monomeric Cu(II) complex consisting of penta and tetra coordinated Cu(II) centers, respectively. Screening tests were conducted to quantify the binding ability of complexes (1 and 2) towards BSA and DNA as well as the protease and nuclease activity of these complexes using gel electrophoresis technique. Furthermore enzyme kinetic studies were also performed for those two complexes towards effectiveness in mimicking catecholase like activities. Overall all the experimental results reveal the potential activity of these copper complexes towards protease, nuclease and catecholase activity. Apart from these, MTT assay was also utilized to scrutinize the anti-proliferative activity which was further investigated using dual staining confocal microscopic images

Copper complexes with a flexible piperazinyl arm: nuclearity driven catecholase activity and interactions with biomolecules

<p>Three new Cu(II) complexes, [Cu(HL¹)(pyridine)(H₂O)](ClO₄)₂·2MeOH (<b>1</b>), [Cu₂(HL¹)₂(NO₃)₂](NO₃)₂·3H₂O (<b>2</b>) and [Cu(HL₂)(NO₃)₂]·MeCN (<b>3</b>), have been synthesized from two Schiff base ligands [HL¹ = 1-phenyl-3-((2-(piperazin-4-yl)ethyl)imino)but-1-en-1-ol and HL² = 4-((2-(piperazin-1-yl)ethyl)imino)pent-2-en-2-ol] using the chair conformer of a flexible piperazinyl moiety. Structural analysis reveals that <b>1</b> and <b>3</b> are monomeric Cu(II) complexes consisting of five- and six-coordinate Cu(II), respectively, whereas <b>2</b> is a dinuclear Cu(II) complex consisting of two different Cu(II) centers, one square planar with the other distorted octahedral. Screening tests were conducted to quantify the binding of <b>1</b>–<b>3</b> towards DNA and BSA as well as the DNA cleavage activity of these complexes using gel electrophoresis. Enzyme kinetic studies were also performed for the complexes mimicking catecholase-like activities. Antibacterial activities of these complexes were also examined towards Methicillin-Resistant <i>Staphylococcus aureus</i> bacteria. The results reflect that <b>2</b> is more active than the monomeric complexes, which is further corroborated by density functional theory study.</p